Immune Monitoring in Infectious Diseases

A deeper understanding of COVID-19 immunity is needed to explore vaccine responses, long-term immunity, predict patients at risk, and even prepare ourselves for a possible new pandemic in the future.

Our unique immune monitoring tools can help you unravel the SARS-CoV-2 specific T-cell immunity in an easy and reproducible way.

We provide four SARS-CoV-2 Packages, each with a curated collection of SARS-CoV-2-specific Dextramer® reagents displaying validated T-cell epitopes. Select the one most suitable for your research:

• SARS-CoV-2 Spike Package
• SARS-CoV-2 A*0201 Package
• SARS-CoV-2 Multi Allele Package
• SARS-CoV-2 Custom Package

For more details, please read here or contact us

Opportunistic viruses can cause severe diseases in immune-compromised patients. Measuring the virus immune status is an important tool to check the risk of infection in immune-compromised patients.

The Virus Dextramer Collection 1 consists of Dextramer reagents, displaying immunodominant, well-characterized epitopes derived from four general and opportunistic viruses: Cytomegalovirus (CMV), Epstein-Barr virus (EBV), Influenza, and BK virus and a negative control Dextramer.

Virus Dextramer® Collection 1 is for research use only.

CMV infection and disease pose a major risk in immunosuppressed patients. Reactivation of CMV is a frequently occurring complication and can contribute to morbidity and mortality if not controlled. CMV-specific CD8+ T cells are considered the main factor in successful management of CMV infection. In transplant patients a low number of CMV-specific CD8+ T cells are predictive for development of CMV-related complications.​

The CMV Dextramer Package consists of Dextramer reagents, displaying immunodominant, well-characterized epitopes derived from CMV-specific antigens and a negative control Dextramer. The CMV Dextramer Package is for research use only. For In Vitro Diagnostics (IVD) use check out the Dextramer® CMV Kit.

* One test is defined as 10 µl MHC Dextramer reagent sufficient to stain up to 1-3 x 10^6 lymphoid cells or 1-3 x 10^5 clonal antigen-specific T cells.

EBV is a persistent virus that infects 90% of the human population. Primary infection may cause acute infectious mononucleosis, and persistent infection may be associated with the development of several malignancies. T cells play a critical role in controlling both the primary and persistent phases of infection.

The package consists of Dextramer® reagents displaying immunodominant, well-characterized epitopes derived from EBV-associated antigens and a negative control Dextramer.

* One test is defined as 10 µl MHC Dextramer reagent sufficient to stain up to 1-3 x 10^6 lymphoid cells or 1-3 x 10^5 clonal antigen-specific T cells.

EBV Dextramer® Package 1 is for research use only.

Send an e-mail to ordering@immudex.com specifying

• Cat. no. of collection or package
• Fluorophore (PE, APC, or FITC) or no Fluorophore (None)

Dextramer® reagents included in the collection and packages are available as single reagents.

Additional virus-specific Dextramer reagents not included in the collections are available.

• Find them here by searching for either "Virus", "CMV", "EBV", or "Influenza" in the category field. Please remember to press clear filter between each search
• Customer-defined cancer-specific Dextramer reagents with your choice of MHC-peptide combination are easily made with MHC alleles from our catalog and with peptides that form stable complexes with the MHC molecule