Immudex

Immudex specializes in detection of antigen-specific T-cells. Immudex produces and sells MHC multimer reagents based on the Dextramer™ Technology.

MHC Dextramer™ reagents are superior for detection of antigen-specific T cells using flow cytometry and immunohistochemistry. 

MHC Dextramer™ Reagents

Efficient detection of antigen specific T-cells depends on sensitive, high quality reagents. The MHC Dextramer™ reagents are a new generation of fluorescent MHC multimers that are particularly efficient in the detection of T-cells carrying T-cell receptors with very low affinity for MHC. The Dextramer™ reagents carry more MHC-molecules and more fluorochromes than conventional MHC multimers and are produced to the highest standards ensuring reproducibility in every experiment. MHC Dextramer™ reagents thus provide the following benefits:

The MHC Dextramer™ reagents can be used to detect antigen-specific T-cells in fluid cell samples (e.g. blood, cultured cell lines, CSF, lymph, synovial fluid) using flow cytometry, or antigen-specific T-cells may be detected in situ in tissue sections.

Fields of application:

• Monitoring vaccine studies
• Monitoring effect of Immunotherapy
• Determination of immune status (e.g. in connection with transplantation and other immunodeficiency)
• Monitoring T-cell responses in infectious disease, cancer, autoimmunity and other malignancies
• Detection of antigen-specific T-cell responses in immunological research