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Stimulate Antigen-Specific T Cells with Xynapse™-T:
- Activation and Expansion: Xynapse™-T enables high-fold clonal expansion of antigen-specific T cells or TCR-engineered T cells, with cytokine production and resulting cell phenotype akin to activation protocols using peptide-pulsed antigen-presenting cells (APCs).
- Flexibility: Xynapse™-T reagents are robust, ready-to-use non-cellular antigen presenting molecules.
- Substitute for APCs: Use Xynapse™-T reagents instead of APCs in potency testing and antigen challenge assays.
- Time saver: No need to pre-culture cells.
- Reliability: Avoid APC-derived biological variation.
Strong Expansion of Antigen-Specific T Cells
Like APCs, Xynapse™-T reagents elicit strong expansion of antigen-specific T cells. That specificity results in an enrichment of relevant T cells that cannot be achieved with aCD3 & aCD28 antibody-based general T cell activation reagents, which indiscriminately stimulate all T cells.
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"Xynapse™ gives us much greater flexibility – we can just do the potency assay tomorrow."
- QC Scientist, TCR-T Cell Therapy Company
"Xynapse™ is a time saver – no need for pre-culturing or preparation of a cell bank."
- QC Scientist, TCR-T Cell Therapy Company