MHC Multimer Proficiency Panel Report 2020
MHC Multimer Proficiency Panel Report 2019
MHC Multimer Proficiency Panel Report 2018
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MHC Multimer Proficiency Testing
Originally developed at the initiative of CIC (the US Cancer Immuno-therapy Consortium of the CRI) and CIMT (the European Association for Cancer Immunotherapy), Immudex offers Proficiency Testing as a non-profit service to help researchers and clinicians worldwide evaluate and benchmark their immune monitoring performance with MHC Multimers.
Using laboratory-specific protocols, antibodies, and flow cytometry, participants determine the number of antigen-specific T cells in provided PBMC samples using MHC multimers and receive a report comparing the results from all participating laboratories.
What You Receive
PBMC samples: identical for all participants*
If requested, MHC Dextramer® reagents free of charge (only pay shipping fees)
Assay instructions
What You Measure
Total number of CD8+ T cells in samples
Number of MHC multimer+ CD8+ T cells in samples
Percent of total CD8+ T cells that are MHC multimer+
MHC Multimer Proficiency Testing Service – Step-by-Step
| SIGN UP | RECEIVE SAMPLES | ANALYZE SAMPLES | UPLOAD DATA | RECEIVE REPORT |
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| Register | PBMCs MHC Dextramer® if requested Assay instructions |
Use your own protocol to analyze PBMC samples according to the instructions | Report your results back to Immudex | Get a report with all participants' performance |
Proficiency Performance 2021
In the MHC Multimer Proficiency Panel 2021, all laboratories received identical PBMC samples for identification of antigen-specific T-cells using MHC multimers, and results were collated to assess the relative accuracy of results across the different laboratories. 13 out of 19 participants (68,4%) had a relative accuracy between 0.66 – 1.5 and were considered to be in “the average range” (dark blue columns).
Learn more in the MHC Multimer Proficiency Panel Report 2021
Performance Reports
Acknowledgement
*Immudex conducts quality control of the PBMC samples before these are shipped to participants.
Participation Fees
| Academia and Non-profit Organizations | To be determined |
| Industry companies and CROs | To be determined |
Registration For 2023 MHC Multimer Proficiency Testing Service
Registration for the MHC Multimer Proficiency Testing Service 2023 opens in Spring 2023. Contact us at proficiencypanel@immudex.com if you’d like to be informed when registration opens.