Investigate Novel Cell Subsets with Customized dCODE Klickmer®

Boosting sensitivity and multiplexing capacity, dCODE Klickmer®​ reagents unlock patterns and changes in the cellular composition of immunity

No Cell Remains Undetected.
Characterize Immune Responses Down to a Single-Cell Level.

Klickmer® reagents broaden the applicability of Dextramer® technology to any cell type of interest by binding and displaying the biotinylated molecule of your choice. Through the application of DNA barcodes, dCODE Klickmer® allows you to identify your target population using NGS or single-cell multi-omics.

With these features, dCODE Klickmer® can, for example, detect multiple antigen-specific, antibody-producing B-cell populations with additional information of the BCR sequence in a single sample as the basis for large-scale antibody discovery.

Read Application Note

A Stable Reagent for Any Fast-Paced, Cutting-Edge Immunology Lab

dCODE Klickmer® was designed to eliminate barriers and shed light on the diversity of cell populations in the immune system. The rapid production turnaround and ease of customization make them ideal for labs looking to push the limits in immunity research.

The high avidity deeply characterizes your target of choice in one sample, one workflow, and without missing valuable information. The compatibility with the 10x Chromium and BD Rhapsody™ systems connects insights about gene expression, surface proteins, and VDJ sequences with single-cell antigen specificity.

One Sample. Endless Insights

Unlock the crucial details of complex immune responses with a flexible detection reagent that reveals high-resolution cell diversity

Other dCODE Klickmer® and dCODE Dextramer® Products

Besides dCODE Klickmer®, Immudex provides ready-to-use and customizable dCODE Dextramer® reagents for high-resolution detection of T cells

MHC I or II dCODE Dextramer®

Ready-to-use reagents for detection of CD8+ or CD4+ antigen-specific T cells.

U-Load dCODE Dextramer® 

Produced in your own lab to detect T cells with your specificity of choice.

CD1d dCODE Dextramer® 

For the detection of NKT Cells.

MR1 dCODE Dextramer®

Ready-to-use reagents for detection of antigen-specific MAIT cells.

dCODE® FITC or APC

dCODE® reagents with FITC or APC fluorochromes available via Custom Solutions and Services.

If you are looking for something but cannot find it in our standard portfolio, we also offer Custom Solutions and Services. Please contact us.

Order dCODE Klickmer®

To order dCODE Klickmer®, please send an e-mail to [email protected] specifying: 

  1. If you are interested in single reagents or panels
  2. The product volume and number of specificities (number of different molecule-specific DNA oligo barcodes) you need.
dCODE Klickmer® Volume Number of Specificities
Single Reagent 30, 60, or 180 µl 1-15
Panel 30 or 60 µl 16, 32, 48, 64, 80, 96, 96 x n

Please note: dCODE Klickmer® is available as a standard product with the PE fluorochrome, or with FITC or APC fluorochromes (or no fluorochrome) via Custom Solutions and Services.

For pricing information, please contact us.

The dCODE® technology is disclosed in granted and pending patents within the WO 2015/185067 and WO 2015/188839 patent families including US11402373, US11585806, US11668705, EP3152232, EP3155426, HK1236546 B, AU2015271324, AU2019264685, AU2021204496, CA2951325, SG11201610177U, JP6956632 and JP7271465.