Application Notes

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Simultaneous phenotype, gene expression, and TCR sequence analysis of 5-OP-RU-specific MAIT cells

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Analyze the Response of SARS-CoV-2 Spike-Specific B Cells to Using Klickmer® Technology

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Maximize the Potential of TCR-T Cell Therapy with Antigen-Specific Solutions and Dextramer® Technology

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Advancing TCR Discovery – Dextramer® Technology for Discovery of TCRs with Greater Therapeutic Value

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Monitoring Long Term T-Cell Immunity In COVID-19 using SARS-CoV-2 Dextramer® Panels

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Single-Cell Evaluation Using dCODE Dextramer® Reagents and 10x Genomics Feature Barcode Protocol

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Uncover antigen-specific immune cell responses and provide new insights in vaccine development

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Identification of antigen-specific B cells at single-cell level for antibody discovery with dCODE® Klickmer

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Case Studies

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Dextramer CMV Kit used in Clinical Study on CMV Reactivation Risk after Allo-HCST Transplantation

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Human liver CD14+CD8+ T cells enriched in cellular immune responses to hepatitis B virus and cancer

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Stringent identification and enumeration of a transient TCR T cell product for in vivo activity assessment

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Immunophenotype and Persistence of T Cells in Phase I Trial of TCR-T Cell Therapy Targeting MAGE-A4

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Validation of MAIT Cells with TCRs Engineered to Recognize HBV infected cells using MHC Dextramer®​

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Screening for Cross-Reactivity and Validation of PC-CAR T Cells using MHC Dextramer®​

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Identifying Shared Tumor Epitopes for High Avidity Cytotoxic TILs using MHC Dextramer®

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Exploring Neoantigen Cancer Vaccines and Checkpoint Inhibitors with MHC Dextramer®

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Identification of Epitope Targets for Vaccination and T-cell Therapies with Klickmer®

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Measurement of SARS-CoV-2 T-cell Responses in Patient Samples with MHC I Dextramer®

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Capturing Primary and Secondary Anti-Yellow Fever T-Cell Responses with MHC I Dextramer®

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Investigating the Effect of Therapeutic Peptide on Tumor-Infiltrating Leukocytes

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CD8+ T-Cell Signature in Acute SARS-CoV-2 Infection Identifies Memory Precursors

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Efficient In-situ Detection of Antigen-Specific, Autoreactive CD4+ T Cells with MHC II Dextramer®

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Plasmacytoid Dendritic Cell Line-Based Vaccine Primes and Expands Antitumor T Cells in Melanoma Patients

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A New TCR-Accepting T-Cell (TnT) Platform to Profile Tumor-Specific T-Cell Receptors

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Assessing the HLA-Specificity of CAR-T Cells with MHC I Dextramer® Reagents

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Cancer Neoepitopes for Immunotherapy: Developing Strategies for Adoptive T-Cell Therapy

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CD8+ T-Cell signature in acute SARS-CoV-2 infection identifies memory precursors

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Superior detection of self-reactive, antigen-specific T-cells using Klickmer® compared to tetramers

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Supporting novel insights into autoimmune type 1 diabetes and adaptive immunity

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Assessment of the safety and efficacy of a novel vaccine in high-grade glioma patients with Dextramer®

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Evaluation of efficacy and immunity following vaccination with an RNA cancer vaccine

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Support the stratification of antiviral treatment after allogeneic hematopoietic cell transplantation

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Mapping of the SARS-CoV-2 epitope-specific T-cell response using dCODE Dextramer®

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dCODE Dextramer® (HiT) allows multiplexing Screening of large epitope panels

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Epitope-specific T-cell response in a cohort of COVID-19 recovered patients using MHC I Dextramer®

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Single-cell level characterization of T cells with dCODE Dextramer® and BD Rhapsody

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Single-cell level identification of antigen-specific T cells with dCODE Dextramer®

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Guides

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Getting Started with Dextramer® Flow Cytometry Data Analysis in FlowJo™ Software (BD Life Sciences)

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dCODE Dextramer® Compatible with 10x Genomics Single Cell Immune Profiling

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Posters

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Single-Cell Multi-Omics Analysis of the SARS-CoV-2 Immune Response Using U-Load dCODE Dextramer®

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Identification of functional MAIT-specific TCRs using MR1 dCODE Dextramer® reagents

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TCR Discovery and Detection of Antigen-Presentation on Cells using the Dextramer® Technology

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Dissecting MAIT cell phenotype and TCR sequences using single-cell RNA sequencing

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Extended antigen specific cellular responses by single-cell immune profiling using dCODE® technology

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Production of High Quality MHC and TCR Monomers and their Applications in Immunological Research

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Discovery of antigen-specific B-cell and T-cell clonotypes using a multiplexed dCODE Dextramer®-based workflow

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TCR Dextramer® reagents can measure antigen presentation on peptide-pulsed cells and PBMCs

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Profiling antigen-specific B cells and CD4+/CD8+ T cells after SARS-CoV-2 infection and vaccination

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Profiling of the antigen-specific immune response using Dextramer® and dCODE® reagents (10x)

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Antigen-Specific Solutions for T-Cell Therapy Development and Manufacturing

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Monitoring of naturally acquired and vaccine induced SARS-CoV-2 Specific CD8+ T cells

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Rapid Klickmer® assay for detection of SARS-CoV-2 Spike-Specific B cells upon Vaccination

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Proficiency Panels: Testing and Confirming Global MHC Multimer Consistency Between Labs in 2021

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Proficiency Panels: Testing and Confirming Global ELISpot Consistency Between Labs in 2021

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Advancements in single-cell multiomic profiling of antigen-specific T cells with dCODE Dextramer® (RiO)

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Monitoring of vaccine-induced SARS-CoV-2-specific cellular immune responses

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The utility of a Dextramer® assay to detect Borrealia-specific T cells as diagnostic biomarkers of Lyme disease.

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Characterization of antigen-specificity, TCR clonotype, and gene expression of single CD4+ T cells.

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Discover the dCODE Dextramer® technology for T-cell epitope profiling and single cell phenotyping.

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Large panels of dCODE Dextramer® to evaluate antigen-specific T-cell immunity at single-cell level.

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Simultaneous single cell analysis of multiple analytes resolves T-cell populations at high resolution.

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dCODE Dextramer®, a new multimer technology for T-cell epitope profiling and single cell deep phenotyping.

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Multi-omics characterization of T-cell populations at single-cell level with dCODE Dextramer® and BD® AbSeq.

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Monitoring of naturally acquired and vaccine-induced SARS-CoV-2 cellular immune responses.

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Proficiency Panels

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T-cell Elispot Proficiency Panel 2019.

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Evaluation of T-cell assay performance.

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