MHC Dextramer® Technology

The Backbone of High-Quality Cellular Immune Monitoring

 

 

MHC Dextramer® reagents for immune monitoring distinguish themselves from alternative technologies by a dextran backbone carrying an optimized number of MHC-peptide complexes and fluorochomes.

This unique structure increases binding affinity to boost detection of even low-affinity T cells and suppress background staining.

Dextramer Figure

Capture a Clear Picture of the Immune Response

Improve signal-to-noise ratio in flow cytometry runs
Enhance staining intensity with a highly stable reagent
Expand the affinity spectrum of detected T-cell receptors
Achieve accurate and reproducible results
Detect T-cell specificities that other technologies miss

 

MHC Dextramer Figure

Areas of Use

Basic, translational and clinical research in immune-oncology, transplantation, autoimmunity, and infectious disease.

MHC I Dextramer®

Reagents to detect antigen-specific CD8+ T cells

MHC II Dextramer®

Reagents to detect antigen-specific CD4+ T cells