Peptide-Receptive easYmers® MHC I and U-Load® MHC II Monomers
Building blocks to easily explore the richness of immune specificity
Immudex is the proud global distributor of the high-quality easYmers® MHC I monomers powered by immunAware and manufacturer of U-Load MHC II.
easYmers® and U-Load MHC II are formulations of peptide-receptive MHC I and II monomers, which can be used to generate specific MHC-peptide complexes by loading your peptide of choice.
U-Load MHC II Specifications Sheet
Discover U-Load® Technology
Read More Details in Our FAQs
Ultimate Flexibility, Reliable Sensitivity
Build Custom U-Load Dextramer® Reagents
Once prepared, the easYmers® or U-Load® MHC II-peptide complexes can easily be loaded onto fluorescently-labeled U-Load Dextramer® or other lab-developed MHC multimers for detection of antigen-specific CD8+ or CD4+ T cells using flow cytometry.
The Allotype Coverage to Truly Explore Human Immune Diversity
Covering a large spectrum of HLA-A, HLA-B, and HLA-C allotypes found in many world populations, the easYmers® and U-Load® MHC II monomers allow creating specific peptide-allele combinations suitable for epitope and neoepitope screening, mapping of antigen-specific T-cell responses to disease, and assessment of MHC-peptide binding.DISCOVER THE MHC ALLELES LIST
Data obtained from Gonzalez-Galarza et al. (2020) "Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools." Nucleic Acids Res. Jan 8; 48(D1): D783–D788. Courtesy of immunAware
Discover the Step-by-Step Instructions
U-Load Dextramer® Specifications Sheet
MHC I-Peptide Monomer and Fluorescent U-Load Dextramer® MHC I Preparation Protocol
MHC II-Peptide Monomer and Fluorescent U-Load Dextramer® MHC II Preparation Protocol
Order easYmers® MHC I Monomer
Each easYmers® product contains the reagents necessary to load peptides into MHC creating easYmers® MHC I-peptide complexes, validate proper refolding of peptide-loaded easYmers® complexes via flow cytometry, as well as a protocol for the streamlined workflow to load easYmers® MHC I-peptide onto U-Load Dextramer®.
To order easYmers®, please send an e-mail to email@example.com specifying your selection of easYmers® and your desired test size.
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Order U-Load® MHC II Monomer
Each U-Load® MHC II product contains the reagents necessary to load peptide into MHC creating U-Load® MHC II-peptide complexes, including peptide loading component and loading buffer, as well as a protocol for the streamlined workflow to load U-Load® MHC II-peptide onto U-Load Dextramer®.
To order U-Load® MHC II, please send an e-mail to firstname.lastname@example.org specifying your selection of U-Load® MHC II and your desired test size.
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For research use only. Not for use in diagnostic or therapeutic procedures.