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Peptide-Receptive easYmers® MHC I and U-Load® MHC II Monomers

Building blocks to easily explore the richness of immune specificity


Immudex is the proud global distributor of the high-quality easYmers® MHC I monomers powered by immunAware and manufacturer of U-Load MHC II.

easYmers® and U-Load MHC II are formulations of peptide-receptive MHC I and II monomers, which can be used to generate specific MHC-peptide complexes by loading your peptide of choice.

easYmer® Specifications Sheet

U-Load MHC II Specifications Sheet

Discover U-Load® Technology

Read More Details in Our FAQs

Ultimate Flexibility, Reliable Sensitivity

Build Custom U-Load Dextramer® Reagents

Once prepared, the easYmers® or U-Load® MHC II-peptide complexes can easily be loaded onto fluorescently-labeled U-Load Dextramer® or other lab-developed MHC multimers for detection of antigen-specific CD8+ or CD4+ T cells using flow cytometry.

The Allotype Coverage to Truly Explore Human Immune Diversity

Covering a large spectrum of HLA-A, HLA-B, and HLA-C allotypes found in many world populations, the easYmers® and U-Load® MHC II monomers allow creating specific peptide-allele combinations suitable for epitope and neoepitope screening, mapping of antigen-specific T-cell responses to disease, and assessment of MHC-peptide binding.


Data obtained from Gonzalez-Galarza et al. (2020) "Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools." Nucleic Acids Res. Jan 8; 48(D1): D783–D788. Courtesy of immunAware

Discover the Step-by-Step Instructions

U-Load Dextramer® Specifications Sheet

MHC I-Peptide Monomer and Fluorescent U-Load Dextramer® MHC I Preparation Protocol

MHC II-Peptide Monomer and Fluorescent U-Load Dextramer® MHC II Preparation Protocol

Order easYmers® MHC I Monomer

Each easYmers® product contains the reagents necessary to load peptides into MHC creating easYmers® MHC I-peptide complexes, validate proper refolding of peptide-loaded easYmers® complexes via flow cytometry, as well as a protocol for the streamlined workflow to load easYmers® MHC I-peptide onto U-Load Dextramer®.

To order easYmers®, please send an e-mail to specifying your selection of easYmers® and your desired test size.

Number of Tests Price (EUR) Price (USD)
20 310 370
50 775 925
150 1,545 1.855

Order U-Load® MHC II Monomer

Each U-Load® MHC II product contains the reagents necessary to load peptide into MHC creating U-Load® MHC II-peptide complexes, including peptide loading component and loading buffer, as well as a protocol for the streamlined workflow to load U-Load® MHC II-peptide onto U-Load Dextramer®.

To order U-Load® MHC II, please send an e-mail to specifying your selection of U-Load® MHC II and your desired test size.

Number of Tests Price (EUR) Price (USD)
50 925 1.110
150 1,855 2.225


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  15. Nastasi, C., et al., Butyrate and propionate inhibit antigen-specific CD8(+) T cell activation by suppressing IL-12 production by antigen-presenting cells. Sci Rep, 2017. 7(1): p. 14516.
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For research use only. Not for use in diagnostic or therapeutic procedures.