MHC Multimer Proficiency Panel

In collaboration with CIC (the US Cancer Immuno-therapy Consortium of the CRI) and CIMT (the European Association for Cancer Immunotherapy), Immudex offers Proficiency Panels as a non-profit service to help researchers and clinicians worldwide evaluate and compare their immune monitoring performance with MHC Multimers.

Using laboratory-specific protocols, antibodies, and flow cytometry, participants determine the number of antigen-specific T cells in provided PBMC samples using MHC multimers and receive a report comparing the results from all participating laboratories.

What You Receive

PBMC samples: identical for all participants*
If requested, MHC Dextramer® reagents free of charge (only pay shipping fees)
Assay instructions

What You Measure

Total number of CD8+ T cells in samples
Number of MHC multimer+ CD8+ T cells in samples
Percent of total CD8+ T cells that are MHC multimer+

MHC Multimer Proficiency Panel – Step-by-Step

 

SIGN UP RECEIVE SAMPLES ANALYZE SAMPLES UPLOAD DATA RECEIVE REPORT
Register PBMCs

MHC Dextramer® if requested

Assay instructions
Use your own protocol to analyze PBMC samples according to the instructions Report your results back to Immudex Get a report with all participants' performance
Registration opens Autumn 2022

Proficiency Performance 2021

In the MHC Multimer Proficiency Panel 2021, all laboratories received identical PBMC samples for identification of antigen-specific T-cells using MHC multimers, and results were collated to assess the relative accuracy of results across the different laboratories. 13 out of 19 participants (68,4%) had a relative accuracy between 0.66 – 1.5 and were considered to be in “the average range” (dark blue columns).

Learn more in the MHC Multimer Proficiency Panel Report 2021

 

Acknowledgement 

*Immudex conducts quality control of the PBMC samples before these are shipped to participants.

Participation Fees

Academia and Non-profit Organizations 1400 EUR / 1600 USD
Zero-revenue biotech companies 1850 EUR / 2100 USD
Positive-revenue biotech companies 2450 EUR / 2800 USD
Pharmaceutical companies and CROs 2750 EUR / 3150 USD

 

Registration For 2022 MHC Multimer Proficiency Panel

Registration for the MHC Multimer Proficiency Panel 2022 opens in Autumn 2022. Contact us at customer@immudex.com if you’d like to be informed when registration opens.

If you have any questions about the MHC Multimer Proficiency Panel, please write to us at proficiencypanel@immudex.com.