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Reliable tools to detect antigen presentation
- Your TCR, our expertise: Our dedicated team of experts produces your TCR candidates as TCR Dextramer® reagents for APC detection by flow cytometry.
- Rigorous Quality Control: The specificity and functionality of each TCR Dextramer® reagent is controlled, making it the safe choice for your research.
- High avidity: Dextramer® technology ensures that even low-affinity pMHC-TCR pairs are reliably detected.
- Inform therapy development: Gain valuable insights into tissue-specific antigen presentation for toxicity prediction or patient stratification.
Understanding the distribution of antigen-specific cells (APCs) in biological samples supports the development of more targeted therapies. However, accurate detection of APCs requires high-avidity tools. Our Custom Solutions and Services team design and manufacture TCR Dextramer® reagents based on your TCR of choice.
Benefiting from the high avidity of Dextramer® Technology, TCR Dextramer® reagents allow you to detect APPCs in target and other tissues by flow cytometry, or potentially in situ hybridization. Sensitive assays for the detection of antigen-presenting cells can help to ensure that the target antigen is present predominantly in the target tissue. This information serves to avoid side effects or toxicity, as well as to select patients for inclusion in clinical trials.
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"I am very happy with the quality of the products and the prompt response by the customer team."
- Scientist, Pharmaceutical Company