dCODE Dextramer® (RiO)
Combine Antigen-specificity With Multi-omics Analysis
dCODE Dextramer® (RiO) reagents are DNA barcoded MHC Dextramer® products
designed to be compatible with BD RhapsodyTM Single-Cell Analysis System
Determine T-cell antigen-specificity at single-cell resolution, providing simultaneous information on gene expression and surface markers expression.
In this example, dCODE Dextramer® (RiO) and BD RhapsodyTM Single-Cell Analysis System were used to detect disease-specific CD4+ T cells within thousands of PBMC and to obtain their gene expression profiling at the single-cell level.Read the Case Study
dCODE Dextramer® (RiO) identified EBV-positive T cells in a PBMC sample (left). The negative control dCODE Dextramer® did not detect any specific cells (right).
Perform simultaneous analysis of antigen specificity, transcriptomic profile, and surface protein expression.
- High-avidity binding to T-cell receptors thanks to multiple MHC-peptide complexes
- Massive multiplexing screening thanks to the unique barcode for each MHC-peptide specificity
- Enrichment of low-frequency cells thanks to PE fluorochromes
- Multiparametric analysis with BD RhapsodyTM Single-Cell Analysis System
Get the most out of your sample
Combine dCODE® Technology with BD's multi-omics solutions and obtain a full immunological profiling in just one workflow
dCODE Dextramer® (RiO) products
- MHC I dCODE Dextramer® (RiO) for the detection of CD8+ antigen-specific T cells. See available MHC alleles
- MHC II dCODE Dextramer® (RiO) for the detection of CD4+ antigen-specific T cells. See available MHC alleles
- dCODE® Klickmer to create personalized dCODE Dextramer® (RiO) by loading your choice of biotinylated molecules (for B-cell research and much more). Read more about dCODE® Klickmer
If you want to hear more about our products, please contact firstname.lastname@example.org
Order dCODE Dextramer® (RiO)
dCODE Dextramer® (RiO) is now available in Europe and will soon be available in the rest of the world.
dCODE Dextramer® (RiO) is available as single reagent or in panels. Discover dCODE Dextramer® grades and test sizes
To order dCODE Dextramer® (RiO) in Europe, please send an e-mail to email@example.com specifying:
- The dCODE Dextramer® grade, Gold or Explore
- Your choice of MHC-peptide combinations. See our list of available MHC alleles
- Test size
- If not otherwise specified, the reagents will be assigned random barcodes. In case you require specific barcodes to avoid overlapping with previous orders, please mention it in your order.
dCODE Dextramer® (RiO) Library Prep Protocol
dCODE Dextramer® (RiO) Product Flyer
dCODE Dextramer® (Rio) Case Study
For research use only. Not for use in diagnostic or therapeutic procedures.
Immudex is the sole manufacturer and provider of dCODE Dextramer® (RiO) reagents, and support related to these products is through Immudex.