MR1 Monomers

High-quality, ready-to-use MR1 Monomers for flexible investigation of ligand-specific MAIT cells

Producing stable, soluble MR1 Monomers with correct folding is challenging due to their complex structure and low-affinity ligands.

By relying on more than 10 years of experience in protein expression, our team of experts has set up an effective manufacturing process with stringent quality control, providing you with high-quality MR1 Monomers.

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Characterize and Investigate MAIT cells with MR1 Monomers

Whether MR1 Monomers, MR1 Dextramer® or MR1 dCODE Dextramer® reagents, Immudex offers two ligands, preloaded into human MR1 Monomers for investigation of ligand-specific mucosal-associated invariant T (MAIT) cells:

  • 5-OP-RU is a potent activator of MAIT cells, from the condensation of microbial 5-A-RU with methylglyoxal
  • 6-FP is a photosynthetic breakdown product of folic acid. As it is non-stimulatory for most MAIT cells it can be used as a negative control.

Custom ligand-MR1 can be requested through Custom Solutions and Services.

The MR1 Product Portfolio

Besides ready-to-use human MR1 Monomers, Immudex also provides MR1 Dextramer® and MR1 dCODE Dextramer® reagents for detection of ligand-specific MAIT cells by flow cytometry, in situ, NGS, and single-cell multi-omics.

MR1 Monomer

 



 

 

 

Optimize for Your Assay of Choice
Human
Biotin
20, 100, 200 µg
5-OP-RU
6-FP

MR1 Dextramer®


 



In situ
Flow cytometry

Human
FITC, PE, APC
25, 50, 150 tests
5-OP-RU
6-FP

MR1 dCODE Dextramer®

Single-cell multi-omics

Human
PE
25, 50 tests
5-OP-RU
6-FP

No Compromises on Quality

We strive to ensure that our products are synonymous with quality. Our products undergo multiple quality checks during production and on finished goods to provide you with the highest quality MR1 Monomers or MR1 Dextramer® reagents.

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Order MR1 Monomers

You can order your MR1 Monomers from the webshop below. Alternatively, please send an e-mail to [email protected] specifying information on:

  • Your preferred reagent format: MR1 Monomer
  • Your preferred ligand; 6-FP and 5-OP-RU
  • Amount

*Higher amounts or test sizes are available upon request.

Questions?

Do you have questions about our MR1 products, implementing our technology into your experimental workflow, protocol optimization, or data analysis and interpretation?

Our technical support team consists of highly skilled scientists that are here to empower you to improve your results, provide you with the tools for success, and share our expertise.