MR1 Monomers

High-quality, ready-to-use MR1 Monomers for flexible investigation of ligand-specific MAIT cells

Producing stable, soluble MR1 Monomers with correct folding is challenging due to their complex structure and low-affinity ligands.

By relying on more than 10 years of experience in protein expression, our team of experts has set up an effective manufacturing process with stringent quality control, providing you with high-quality MR1 Monomers.

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Characterize and Investigate MAIT cells with MR1 Monomers

Whether MR1 Monomers, MR1 Dextramer® or MR1 dCODE Dextramer® reagents, Immudex offers two ligands, preloaded into human MR1 Monomers for investigation of ligand-specific mucosal-associated invariant T (MAIT) cells:

  • 5-OP-RU is a potent activator of MAIT cells, from the condensation of microbial 5-A-RU with methylglyoxal
  • 6-FP is a photosynthetic breakdown product of folic acid. As it is non-stimulatory for most MAIT cells it can be used as a negative control.

Mouse MR1 reagents and custom ligand-MR1 can be requested through Custom Solutions and Services.

The MR1 Product Portfolio

Besides ready-to-use human MR1 Monomers, Immudex also provides MR1 Dextramer® and MR1 dCODE Dextramer® reagents for detection of ligand-specific MAIT cells by flow cytometry, in situ, NGS, and single-cell multi-omics.

MR1 Monomer





Optimize for Your Assay of Choice
20, 100, 200 µg

MR1 Dextramer®


In situ
Flow cytometry

BV421, FITC, PE, APC or none
25, 50, 150 tests

MR1 dCODE Dextramer®

Single-cell multi-omics

25, 50 tests

No Compromises on Quality

We strive to ensure that our products are synonymous with quality. Our products undergo multiple quality checks during production and on finished goods to provide you with the highest quality MR1 Monomers or MR1 Dextramer® reagents.

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Discover Immudex Monomers

MHC Monomers

For interaction with CD4+ and CD8+ T cells


CD1d Monomers

For interaction with lipid-specific iNKT cells


HLA-E and HLA-G Monomers

For interaction with antigen-specific NK and T cells


Order MR1 Monomers

You can order your MR1 Monomers from the webshop below. Alternatively, please send an e-mail to [email protected] specifying information on:

  • Your preferred reagent format: MR1 Monomer
  • Your preferred ligand; 6-FP and 5-OP-RU
  • Amount

*Higher amounts or test sizes are available upon request.


Do you have questions about our MR1 products, implementing our technology into your experimental workflow, protocol optimization, or data analysis and interpretation?

Our technical support team consists of highly skilled scientists that are here to empower you to improve your results, provide you with the tools for success, and share our expertise.

BV421 is equivalent to Brilliant Violet™ 421, which is a trademark or registered trademark of Becton, Dickinson and Company or its affiliates, and is used under license. Powered by BD Innovation.